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Our findings further showed that treatment with C. borivilianum root aqueous extract preserved near normal lipid profile levels in diabetic rats. C. borivilianum root extract has been reported to exhibit anti-hyperlipidemic and hypolipidemic effects . Visavadiya and Narasimhacharya  reported that administration of C. borivilianum root to hypercholesterolemic, non-diabetic male rats resulted in a significant increase in plasma HDL levels and an improvement of plasma and hepatic lipid profile levels. We have shown that administration of C. borivilianum root extract was able to maintain near normal TC, TG, VLDL, LDL and HDL levels in diabetic rats. Preservation of near normal serum lipid profile levels could help to protect against hypercholesterolemia-induced cardiovascular complications including artherosclerosis and coronary artery disease  in view that hypercholesterolemia in diabetes is frequently associated with increased plasma LDL, TG with decreased HDL levels . In addition, the increase insulin secretion as observed in diabetic rats treated with C. borivilianum root extract could help to normalize the lipid profile levels in view that insulin was found to inhibit TC  and TG  syntheses. In our study, negative correlation was observed between TG and TC with serum insulin levels which indicate that changes in serum lipid profiles was dependent on insulin.. The tumors were principally located in the left colon (71.3%) and rectum (33.5%). There were 216 (93.9%) adenocarcinomas buy me a rose lyrics 10 (4.3%) mucinous adenocarcinomas, and 4 other tumors. Most of the carcinomas were pT3 (68.3%) and pT4 (22.2%). There was regional lymph node metastasis in 140 patients. SDC1 expression was identified in the cancer cells of 212 (96.8%) colon cancer cases. Of the SDC1-positive cases, 131 showed predominantly membranous immunopositivity, and 81 showed a predominantly cytoplasmic staining pattern. Mixed membranous and cytoplasmic staining was observed in 154 cases. In 93 cases, stromal SDC1 reactivity was noted. Epithelial SDC1 immunopositivity was significantly associated with tumor size (p = 0.016) and epidermal growth factor receptor expression (p = 0.006). However, it was not significantly correlated with lymph node metastasis, distant metastasis, lymphatic or vascular invasion, or KRAS mutation. In addition, stromal SDC1 immunopositivity was significantly associated with the male sex (p = 0.018)..
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DZP Technologies is a leading developer of specialty materials, formulations, and printing technologies for emerging industries. Founded in 2008, we have been working closely with our customers to create innovative materials for a range of markets, from consumer electronics and wearables, to 3D-printing and renewable energy.
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Haydale Composite Solutions Ltd.
Haydale is a global technology solutions company passionate about creating the next generation of advanced materials by bringing together cutting-edge technology with engineering know-how to enhance the performance of products and materials thus delivering business value for our customers.
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ADVISE-DETA is a new company specialising in the design, construction and installation of in-process dielectric sensors and on-line monitoring and quality assurance systems for composites manufacturing processes. The knowledge and the IP rights of the relevant technology have been transferred to ADVISE-DETA from the Greek company ADVISE, which has a track record of developing quality control systems for advanced manufacturing processes as a result of research projects and bilateral collaborations with leading European and UK composite manufacturers.
The core technology development within ADVISE-DETA lies with interdigital sensors, which have been applied to several fields, among other to cure monitoring, inspection and diagnostics of membranes purifying gases and nanomaterials dispersion in liquids. Around the sensing elements, the company has developed measurement electronics, software tools for data acquisition, modelling, simulation, optimisation and process control.
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Brunel Composites Centre (BCC)
Brunel University London has been highly successful in creating an industrial innovation research resource, named Brunel Composites Centre (BCC), which sits between the knowledge base and industry, supporting partners in industry to transfer academic research into industrial application. BCC is a shared research and technology capability specialising in novel composites processing and joining technologies, applied to industrial environments. It undertakes joint research programmes and aims to develop the next generation of technologies and engineers.
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TWI is one of the world’s foremost independent research and technology organisations, with expertise in materials joining and engineering processes as applied in industry. TWI specialises in innovation, knowledge transfer and solving problems across all aspects of manufacturing, fabrication and whole-life integrity management. Established in Cambridge, UK in 1946, the organisation has gained a first-class reputation for service through its teams of respected consultants, scientists, engineers and support staff. With around 800 employees, it works with over 1800 Industrial Member companies in over 70 countries. TWI currently operates from 54,000 square metres (581,000 square feet) of manufacturing, testing and training space; five UK and 13 overseas facilities serve both its Industrial Membership and its training and examination needs. A successful international Training and Examinations programme sees around 25,000 students trained each year in welding and inspection technologies.
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